We investigate the mechanical properties of the adult stem cells and their extracellular matrix environment in normal and malignant primary human breast tissue.

Our aim is to pinpoint novel therapeutic targets in stem-like breast cancer cells. The focus of our studies is on how mechanotransduction, ie. the mechanical links between the extracellular environment and the cell interior, contributes to breast morphogenesis and de novo oncogenesis. Our research combines advanced imagining techniques and quantitative mechanobiology to investigate fundamental mechanisms in mouse and human mammary gland development and cancer. The research group is led by academy research fellow, Adjunct Professor, Emilia Peuhu.

Read more: https://peuhulab.utu.fi/